THE EFFECT OF HESPERIDIN SUPPLEMENTATION ON BLOOD PRESSURE IN DOXORUBICIN INDUCED CARDIAC TOXICITY IN MALE WISTAR RATS
Abstract
ABSTRACT
This study investigates the effect of hesperidin supplementation on blood pressure and histological changes in doxorubicin-induced cardiac toxicity in male Wistar rats. Doxorubicin is known to cause cardiotoxicity, leading to elevated systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP). In our study, the Doxorubicin group exhibited significant increases in SBP, DBP, and MAP compared to the control group (P
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