ANTIBACTERIAL ACTIVITY OF GARLIC (ALLIUM SATIVUM) AND SCORPION TAIL (HELIOTROPIUM INDICUM ) AGAINST COMMON BACTERIA PATHOGENS

Student: Patience Dawi Abdul
Supervisor: Dr Oyekanmi Bolape Adeola
HOD: Dr Oyekanmi Bolape Adeola
Department of Medical Laboratory Science
Medicine
Adeleke University, Ede, Osun State

Abstract

Medicinal plants have long been utilized as primary sources of treatment in traditional medicine systems worldwide, particularly in regions where access to modern healthcare is limited. This study investigates the antibacterial activity of two such plants, Garlic (Allium sativum) and Scorpion Tail (Heliotropium indicum), against common bacterial pathogens. Garlic is known for its multifaceted therapeutic properties, including antibacterial, antifungal, antiparasitic, hypotensive, and hypolipidemic effects, as well as exhibiting anticancer activity. Similarly, Heliotropium indicum has been traditionally employed to treat various ailments, such as fever, ulcer, inflammation, dermatoses, and rheumatism.The antibacterial activity of Garlic and Scorpion Tail extracts was evaluated against several bacterial strains, including Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa. Results indicated varying degrees of sensitivity to different extracts and bacterial strains. Notably, Garlic extracts demonstrated antibacterialsensitivity towards Staphylococcus aureus, while Scorpion Tail extracts exhibited positive responses against Klebsiella pneumoniae and Staphylococcus aureus. However, variations in efficacy were observed depending on the extraction solvent and concentration . This study underscores the potential of Garlic and Scorpion Tail extracts as alternative or adjunctive therapies against bacterial infections. Further research should be carried out with higher concentrations to investigate the underlying mechanisms of action and optimize extraction protocols to enhance their therapeutic efficacy. Integrating evidence-based herbal medicine into mainstream healthcare systems could provide valuable treatment options, especially in resource-limited settings where traditional medicine remains prevalent.

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