ANTIOXIDATIVE EFFECT OF CURCUMIN IN THE HIPPOCAMPUS OF AN ALBINO WISTER RAT FOLLOWING COBALT ADMINISTRATION IMPACT OF NRF2
Abstract
This study aimed at showing the Antioxidative effect of curcumin in the hippocampus of an
albino wister rat following cobalt administration impact of NRF2 twenty adult albino wister rats
were used for the research. Animals were allotted in four groups comprising of five rat per cage.
Before termination of experiment, neurobehavioral test was carried out following by sacrifice of
the animals using cervical dislocation. Tissue processing was perform using standard
routinHematoxylin and Eosin (H & E) stains. Result showed that there was no decrease in body
weight of curcumin when compared to the final control group body weight. Curcumin and cobalt
at 50 and 240mg/kg showed a decrease in body weight when compared to the body weight in
control group (p
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