INVITRO ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF OCIMUM GRATISSIMUM (SCENT LEAF) EXTRACTS OBTAINED FROM MINNA METROPOLIS
Abstract
Abstract
The study evaluated the in vitro antioxidant activities of Ocimum gratissimum (scent leaf) extract obtained from Minna metropolis. Phytochemical screening revealed high concentrations of phenols (478.50 ± 1.07 mg/100 g), flavonoids (85.19 ± 0.45 mg/100 g), tannins (131.47 ± 1.18 mg/100 g), saponins (125.47 ± 0.59 mg/100 g), and alkaloids (35.18 ± 0.36 mg/100 g). Antioxidant activities were assessed using DPPH radical scavenging, ferric reducing antioxidant power (FRAP), and inhibition of lipid peroxidation assays. The extract exhibited concentration-dependent antioxidant effects across all assays, with higher activities observed at 200 µg/mL compared to lower concentrations. Although the activities were significantly (P < 0.05) lower than those of ascorbic acid, the extract demonstrated considerable free radical scavenging and reducing capacities. The findings suggest that Ocimum gratissimum leaves contain potent natural
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