IN VITRO EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF ETHANOL EXTRACT OF CRATEROSIPHON SCANDENS STEM BARK

Student: Emmanuel Ndukwe Ukpai
Supervisor: Dr O C Enechi
HOD: Dr Anosike Joy
Department of Biochemistry
Natural Science and Environmental Studies
Godfrey Okoye University, Ugwuomu-Nike, Enugu, Enugu State

Abstract

The study looked at how Craterosiphon scandens stem bark extract affected proteinase activity, heat-induced hemolysis, albumin denaturation, and calcium chloride-induced platelet aggregation in order to assess its potential anti-inflammatory properties in vitro. Utilising gas chromatography and mass spectroscopy, the bioactive components in the extract were found. The outcome shown that, in comparison to the control, various ethanol extract concentrations (31.25, 62.5, 125, and 250 mg/ml) and the common inflammatory medication (ibuprofen) effectively (p

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