ANTIMICROBIAL ACTIVITY OF MORINGA OLEIFERA LEAVE EXTRACT ON GRAM NEGATIVE BACTERIA
Abstract
ABSTRACT
The aim of the present study was to investigate the phytochemical constituents and evaluate the antibacterial activity of Moringa oleifera leaf extracts, against Escherichia coli and Salmonella typhi. The bioactive compounds are extracted from M. oleifera leaves by using solvents, ethanol and water. The qualitative phytochemical analysis of M. oleifera leaves were carried out using standard procedures to identify the constituents of bioactive compounds (Alkaloids. Flavonoids, Tannins, Saponnins, glycosides, Alkaloids and Phenols). The ethanol crude leaves extract were used to determine the Minimum Inhibitory Concentration on E. coli and S. typhi by using the method of Greenwood as well as the inhibitory zone. Results, this study showed that the extract is active against bacterial isolates, whereas the inhibitory effect of the isolate depends on concentration. Also, the sensitivity of the bacterial isolate to the ethanolic and aqueous extract differs whereas E. coli is more sensitive to the extract with zone of inhibition 9.0mm and 4.0mm while S typhi is less sensitive with zone of inhibition 7.0mm and 3.0mm respectively in comparison with a control.
Full-Text Access Notice
In accordance with the NERD Policy on promoting peer-reviewed publication, public access to the full text of a project, thesis or dissertation is restricted for three years, allowing the author and supervisors sufficient time to pursue peer-reviewed publication.
During this period, researchers with legitimate academic or research purposes may request authorisation directly from the author to enable NERD to release the indexed full texts of the work using the form below.