ANTIMICROBIAL ACTIVITY OF (CARICA PAPAYA) PAWPAW SEED EXTRACTS AGAINST SELECTED MICRO ORGANISM WITHIN LOKOJA METROPOLIS, KOGI STATE, NIGERIA

Medicinal plants are well-known natural sources of remedies, used in the treatment of innumerable diseases since antiquity. Wide range of medicinal plant extracts are used to treat several infections as they have potential antimicrobial activity. This study was aimed to investigate antibacterial activity of Carica papaya seed with ethanol as solvents against Gram negative and Gram-positive bacteria. The seeds of Carica papaya were dried, powdered and extracted with Ethanol. Disc diffusion method was used for the antibacterial assay and measuring the zone of inhibition. The percent yield of crude extract 4% was obtained from Carica papaya Seed with, Ethanol as solvents while, the Crude extracts from the Carica papaya Seed showed antibacterial activity. Carica papaya Seed with Ethanol extract exhibited the following antibacterial activity. Staphylococcus on concentration serial concentration of 0.2,0.4,0.6 and 0.8had inhibition zones of 23 mm, 11 mm, 11 mm and 22 mm of respectively and Salmonella Typhi on concentration serial concentration of 0.2,0.4,0.6 and 0.8 had inhibition zones of 21 mm,11 mm, 15 mm and 12 mm of respectively and E. coil on concentration serial concentration of 0.2,0.4,0.6 and 0. 8 had inhibition zones of 50 mm, 12 mm, 35 mm and 12 mm of respectively. In conclusion, this study is limited to the seed parts of Carica papaya which was tested for its antimicrobial activity. So, the same work should be carried out on different parts of Carica papaya plant like; bark, root, leaves, flower and fruits on antibacterial activities so, as to have a clear picture of the spectrum of antibacterial activity of the plant.