ANTIMICROBIAL ACTIVITIES OF PERSEA AMERICANA (AVOCADO) SEED EXTRACT AGAINST PROTEUS, KLEBSIELLA AND CANDIDA ALBICANS
Abstract
Abstract
The increasing prevalence of antimicrobial resistance has necessitated the exploration of alternative therapeutic agents, particularly from plant sources. This study investigated the antimicrobial activity of Persea americana (avocado) seed extracts against Klebsiella spp., Proteus spp., and Candida albicans. Methanolic and ethanolic extracts were prepared and evaluated using disc diffusion and minimum inhibitory concentration (MIC) methods. Phytochemical analysis revealed the presence of tannins, flavonoids, phenols, saponins, alkaloids, terpenoids, and glycosides. The extracts showed dose-dependent antimicrobial activity, with inhibition zones ranging from 8.10 mm to 18.70 mm. MIC values indicated effective inhibition at concentrations ≥50%. The findings suggest that avocado seed extracts possess significant antimicrobial properties.
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