EVALUATION OF LOCAL ANALGESIC ACTIVITY OF QUASSIA UNDULATA ETHANOLIC AND METHANOLIC EXTRACT IN MICE

Student: Elsie Anulika Emeto
Supervisor: Miss Efejene Ofejiro Israel
HOD: Dr Chinedu Enegide
Department of Pharmacology
Health Sciences
Novena University, Ogume, Delta State

Abstract

Quassia undulata is a perennial medicinal plant species belonging to the family simaroubaceae it is mostly used in traditional medicine for treatment and management of a wide range of disease The aim of this study is to investigate the potential pain reliving effect of ethanolic and methanolic extracts of quaasia undulata when applied locally in mice, The methods used for this study includes extraction process phytochemical analysis acute toxicity test (LD50) . drug and chemicals. The annigesic activity of the extracts was assessed using acetic acid induced writhing by 73.6% at 200mg/kg, (p

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