ANTIMICROBIAL ACTIVITY OF VERNONIA AMYGDALINA (BITTER LEAF) EXTRACT AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS
Abstract
ABSTRACT
Methicillin-Resistant Staphylococcus aureus (MRSA) is a significant public health concern due to its resistance to common antibiotics. This study explored the antimicrobial potential of Vernonia amygdalina (bitter leaf) extract against MRSA. Phytochemical screening of the extract revealed the presence of active compounds such as flavonoids, alkaloids, tannins, and saponins. However, laboratory assays, including agar well diffusion and minimum inhibitory concentration (MIC), demonstrated no zone of inhibition, indicating that the extract did not effectively inhibit MRSA growth at the concentrations tested. These findings suggest that Vernonia amygdalina may not possess significant antimicrobial activity against MRSA in this study.
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