EFFECT OF HELLENIA SPECIOSA STEM EXTRACT ON THE LIVER MARKER ENZYMES OF STZ INDUCED DIABETES OF ALBINO RATS

Student: Goodness Bufa Tawo
Supervisor: Dr Bayim Peter Robins Bayim
HOD: Dr Bayim Peter
Department of Biochemistry
Physical Sciences
University of Cross River State, Calabar

Abstract

Liver disorders are common and are traditionally treated by medicinal plants especially in rural areas where they are widely available. Generally, medicinal plants play a key role in the healthcare systems around the world and one of such plants is Hellenia speciosa. Hellenia speciosa (J.Koenig) S.R. Dutta is a plant species belonging to the family Costaceae. In Ayurveda, the rhizome of this plant has been extensively used to treat fever, asthma, and intestinal worms. In this study, we aimed at evaluating the effect of Hellenia speciosa extracts on liver marker enzymes of streptozotocin induce diabetes of albino rat. Thirty-six (36) Albino Wistar rats were divided into groups; control groups and experimental group with each group having six (6) rats. Diabetes was induced by intraperitoneal injection of streptozotocin (1mg/kg body weight), and the treatment of the rats lasted for 14 days. According to our results, ALT levels showed no significant difference (p

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