EVALUATION OF SYSTEMIC INFLAMMATORY INDEX AND SYSTEMIC INFLAMMATORY RESPONSE IN PREGNANT WOMEN
Abstract
This study looked into the Systemic Inflammatory Index (SII) and the Systemic Inflammation Response Index (SIRI) as biomarkers for inflammation and possible pregnancy complications. The research was a descriptive cross-sectional study conducted at Central Hospital in Agbor, Delta State. Venous blood samples were taken from both pregnant and non-pregnant women and were analyzed using a 5-part hematology analyzer. Findings showed that pregnant women had notably higher levels of SII and SIRI compared to non-pregnant women, indicating an increase in systemic inflammation during pregnancy. There were significant differences between trimesters, with the third trimester showing the highest levels of SII and SIRI. Positive correlations were identified between systolic blood pressure, fasting glucose, SII, and SIRI, while diastolic pressure had a negative correlation. These results suggest that SII and SIRI are higher during pregnancy and might be helpful non-invasive tools for monitoring inflammation and predicting complications related to pregnancy
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