EFFECT OF ETHANOL LEAF EXTRACT OF CEIBA PENTANDRA ON FOOD INTAKE, WATER INTAKE AND BODY WEIGHT CHANGES IN WISTAR RATS

Student: Nguper John Yateghtegh
Supervisor: Dr Benjamin U. Idam
HOD: Dr Ujong Gabriel
Department of Human Physiology
Basic Medical Sciences
University of Cross River State, Calabar

Abstract

The effect of oral administration of ethanol leaf extract of Ceiba pentandra on food intake, water intake and body weight changes in Wistar rats was investigated. Fresh leaves of Ceiba pentandra were collected and ethanol samples of the extract were prepared. A total of 15 rats were used. The rats were divided into three groups comprising group 1 (control), group 2 and group 3. The rats in group 2 and group 3 were administered 400mg/kg and 800mg/kg of Ceiba pentandra leaf extract respectively orally, while the control group received no treatment. All the animals had free access to feed and water. At the end of a 30-day period, the animals were assayed for food/water intake and body weight changes. Daily food and water intake in all the groups were recorded. Initial and final body weight of each animal was also ascertained. The results obtained showed a significant (P

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