MODULATORY EFFECTS OF METHANOLIC EXTRACT OF AIDAN FRUITON INTESTINAL TRANSIT AND FECAL COMPOSITION
Abstract
The effectoforaladministration ofmethanolic extractofAidan fruit on fecal compositionandintestinaltransitinWistarratswasinvestigated.TheAidanfruitswere collectedandthemethanolicextractswereprepared.Atotalof15ratswereused.The ratsweredividedintothreegroupscomprisingofthecontrolgroup,group2andgroup 3.Theratsingroup2andgroup3wereadministered400mg/kgand800mg/kgofthe methanolicextractofAidanfruitrespectivelyorally,whilethecontrolgroupreceived 0.2mlofdistilled water.Allthe animals had free access to feed and water.The treatmentlastedfor14daysafterwhichtheanimalsweresacrificedandassayedfor fecalcomposition(protein,glucoseandcholesterol),andintestinaltransit(lengthof smallintestine,distance traveled by charcoalmeal,percentage ofmovementof charcoalmeal,andpercentageinhibitionofmotility).Allgroupswerefedwithnormal ratfeedandallowedfreeaccesstowater.Resultofthestudiesonfecalsamples showed significant(P
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