LEVELS OF CREATINE KINASE AND LACTATE DEHYDROGENASE IN POSTMORTEM VITREOUS OF RABBITS IN DEATHS BY BLEACH TOXICITY AND DISGUISED AS BLEACH TOXICITY

Accurate determination of cause of death is critical in forensic investigations, particularly in cases involving chemical exposure. This study aimed to evaluate postmortem levels of creatine kinase (CK) and lactate dehydrogenase (LDH) in the vitreous humor of rabbits in deaths caused by bleach toxicity and deaths intentionally disguised to mimic bleach toxicity. Adult rabbits were randomly assigned into two groups: one group subjected to lethal bleach exposure to induce true bleach toxicity deaths, and the second group subjected to disguised bleaching toxicity ( strangulation before bleach administration ). After death, vitreous humor was carefully collected under sterile conditions, and CK and LDH concentrations were measured using standard biochemical assays. The findings showed significant differences in enzyme levels between the two groups, with true bleach toxicity deaths exhibiting distinct CK and LDH profiles. These results suggest that postmortem enzyme analysis in vitreous humor can reliably differentiate genuine from disguised bleach-related fatalities, highlighting its potential application as a supplementary tool in forensic pathology. Keywords: vitreous humor, creatine kinase, lactase dehydrogenase, homicide.