SICKLE CELL CRISES PREDICTION SYSTEM

Student: Franklin Chukwuebuka Maduabuchi
Supervisor: Prof Nyangwarimam Ali
HOD: Prof Nyangwarimam Ali
Department of Computer Engineering
Engineering
Nile University of Nigeria, Abuja

Abstract

This project presents the design and development of, a wearable health monitoring system aimed at predicting and managing sickle cell crises. The system integrates real-time monitoring of vital signs such as SpO₂, body temperature, and hydration status, alongside demographic risk factors like age and gender. A machine learning model processes these parameters to predict crisis onset with high accuracy, providing early warnings to patients and caregivers. The system's architecture includes a wearable device that collects physiological data, a mobile application for real-time monitoring and alerts, and a web interface for caregiver oversight. A key feature is the predictive model, built using an ensemble approach combining Logistic Regression, Random Forest, and XGBoost, with a focus on stability and generalizability. The model was trained using a dataset of sickle cell patients, and its performance was evaluated through metrics such as ROC AUC, F1 Score, precision, and recall, yielding promising results in both classification and real-time prediction tasks.

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