ANTI-INELAMMATORY AND ANALGESIC SEFECTS OF METHANOLIC EXTRACT OF AIDAN FRUITS IN WISTAR RATS

Student: Uduak-Obong Daniel Akpan
Supervisor: Dr Victoria Okon
HOD: Dr Gabriel Ujong
Department of Physiology
Basic Medical Sciences
University of Cross River State, Calabar

Abstract

This present study is aimed at investigating the anti-inflammatory and analgesic effect of methane extract of adian fruit in wistar rats. Fifteen (15) male wistar rats of body weight (90-150g) were u: in this research work. The rats were assigned to three experimental group (n=5) as follows: grou Normal control (NC) group received 0.2m of distilled water and feed, group ii: Aidan fruit high d group received 800/kg/day. group iii: Adian fruit low dose group received 400mg/kg/day. All groups were treated orally for 14 days after which the animals were sacrificed. The result shov that in the number of writhes per 30 minutes in the test groups were significantly decreased (p=0. when compared to the control group. The percentage inhibition of pain in the test groups w significantly increased (p

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