COMBINED EFFECT OF 10% ROASTED SESAME SEED (SESAMUM INDICUM) DIET AND TURMERIC (CURCUMA LONGA) ON LIVER FUNCTION IN STREPTOZOTOCIN INDUCED DIABETIC RATS

Student: Theophilus Unimawhu Abang
Supervisor: Dr Ugwu Melvin
HOD: Dr Kayode Dasofunjo
Department of Medical Biochemistry
Basic Medical Sciences
University of Cross River State, Calabar

Abstract

The study of the evaluation of combined effect of 10% roasted sesame seed (sesamum indicum) diet and turmeric (curcuma longa) on liver function in streptozotocin induced diabetic rats was investigated. a total of forty (40) wistar rats were used but they were divided into groups with each groups having five (5). group1 was the normal control (nc), group 2: diabetic control (dc), group 3 standard drug (std), group 4 10% roasted beni seed, group 5 diabetic + 10% roasted beni seed, group 6 200mg tumeric, group 7 diabetic + 200mg tumeric, group 8: diabetic + 200mg tumeric + 10% roasted beni seed.at the expiration of the experiment, liver tissue was collected the liver was homogenized and centrifuged and supernatant was collected. biochemical assays total protein, serum albumin, direct bilirubin, total bilirubin was carried using standard methods. the result of total protein activity in the wistar rats showed a significant (p

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