EFFECT OF LEACHED STYRENE INTO FOOD ON SERUM TOTAL PROTEIN OF NORMAL ALBINO WHISTER RATS

ABSTRACT this study investigates the effects of leached styrene from food packaging on serum total protein levels in albino Wistar rats. Two groups of rats were observed: Group I, which served as the control, and Group II, which was exposed to styrene leached into food. The results indicated a Hecrease in the total protein levels in the styrene-exposed group (Group ) compared to the control oroup. Group I exhibited a total protein level of 64.10+0.1 l g/L, whereas Group Il showed a reduced total protein of 61.00+2.56 g/L. This imply a potential negative effect of styrene on protein synthesis or metabolism. Albumin levels were also affected, with Group I recording an albumin poncentration of 29,2 1#1.20 g/L, while Group II showed a significantly higher albumin level of 34.01+1.86 g/L. This could indicate a compensatory response or an imbalance in protein distribution between albumin and globulin due to styrene exposure. Interesting, globulin levels remained undetectable (0.00:+0.00 g/L) in both groups, highlighting no variation in this fraction between the control and treated groups. Further research is necessary to explore the long-term effects of styrene on protein synthesis and the broader implications for health, particularly focusing Dn other protein fractions and their roles in honmeostasis.