EFFECT OF MECHANIC LEACHATE ON THE OVARY OF FEMALE WISTAR RAT
Abstract
Mechanic leachate refers to the mixture of hazardous chemicals and contaminants, such as heavy
metals, hydrocarbons, and spent engine oils, that are released into the environment from
automotive repair activities. These substances pose significant risks to both environmental and
public health, particularly when they infiltrate water sources or accumulate in soil.
Therefore, this work seeks to investigate the effect of mechanic leachate on the ovaries of female
Wistar rats, focusing on the total body and ovary weights and histopathological changes.
Twenty-five female (25) Wistar rats were used, divided into five groups (n=5) with varying
levels of exposure to mechanic leachate. The study involved detailed histopathological analysis
of the ovarian tissues post-exposure, along with evaluations of health parameters, including body
and organ weight analyses.
The results indicated significant ovarian damage in the rats exposed to mechanic leachate.
Observed histopathological changes included degeneration of follicles, increased follicular
atresia, and inflammation. Additionally, there were broader health impacts, such as weight loss
and disrupted reproductive cycles.
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