ASSESSMENT OF RED CELL INDICES OF PREGNANT WOMEN AT DIFFERENT TRIMESTERS OF PREGNANCY ATTENDING NDUTH, OKOLOBIRI, BAYELSA STATE.

Student: Michael Friday Mieseigha
Supervisor: Prof Ferdinand Chukwuma Ezeiruaku
HOD: Dr Tolulope Oluwakemi Alade
Department of Medical Laboratory Science
Basic Medical Sciences
Niger Delta University, Wilberforce Island, Bayelsa State

Abstract

This study evaluates the red cell indices of pregnant women attending NDUTH, Okolobiri, Bayelsa State, during various trimesters of their pregnancy. the red cell indices including MCV, MCH, MCHC, PCV, and Hb, in pregnant women across different trimesters. A total of 80 subjects were recruited for the study, comprising a control group and a test group. The control group consisted of 20 non-pregnant women, whereas the test group consisted of 60 pregnant women (20 from each of the three trimesters of pregnancy). Test of significance was done using one-way analysis of variance (one-way ANOVA), followed by post-hoc analysis (multiple comparison test). The statistical significance was set at P < 0.05. The results were expressed as mean ± standard deviation. Overall, the study revealed a progressive decrease in MCV from the 1st to the 3rd trimester, with non-significant changes in MCH and MCHC values. The PCV and HB levels showed a significant decrease as pregnancy progressed from the 1st to the 3rd trimester. The research revealed varying trends in the mean values of these red cell indices throughout pregnancy. While there were no statistically significant differences in MCV, MCH, and MCHC values across trimesters, significant differences were observed in PCV and Hb levels. The findings suggest dynamic changes in red cell indices during pregnancy, highlighting the importance of monitoring these parameters to ensure maternal and foetal well-being.

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