THE PERCENT DPPH INHIBITING POTENTIALS OF AQUEOUS METHANOL EXTRACT OF PHYLLANTHUS AMARUS SCHUMACH. & THONN.
Abstract
Medicinal plants are a valuable source of natural antioxidants, which play a vital role in protecting against oxidative stress related diseases. Phyllanthus amarus Schum. & Thonn., a medicinal herb widely used in traditional medicine. In this study, the antioxidant potential of the aqueous methanol extract of Phyllanthus amarus was evaluated using the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay. The extract demonstrated a concentration-dependent increase in antioxidant activity, with an IC₅₀ value of 133.73 ± 6.32 µg/mL, while gallic acid, used as the standard, exhibited a significantly lower IC₅₀ of 107.27 ± 4.32 µg/mL (p < 0.05). Although less potent than gallic acid, the extract showed moderate radical scavenging ability, attributable to its phytochemical constituents. These findings provide scientific support for the traditional use of Phyllanthus amarus and suggest that it may serve as a promising source of natural antioxidants for the prevention and management of oxidative stress related disorders.
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