ANTIMICROBIAL ACTIVITY OF SEED EXTRACT OF PIPER GUINEENSE (LOCAL UZIZA) ON ESCHERICHIA COLI, STAPHYLOCOCCUS SP. AND SALMONELLA SP.
Abstract
ABSTRACT
Piper guineense is a medicinal plant that has wide application in African traditional medicine where it is often used in the treatment of bacterial and fungal infections. It is an economic plant with numerous health benefits which is also consumed regularly as a functional food. Based on its numerous ethno-botanical, traditional and economic uses, it became interesting to evaluate the bioactive compounds present in the extracts and to further screen the extracts against some selected human pathogenic bacterial and fungal strains so as to ascertain the efficacy of the extracts and its compounds as potent antibacterial and antifungal lead compounds. The result of the present study demonstrates that P. guineense extracts contain antibacterial and antifungal compounds that may be useful for the discovery of new antibiotics.
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