STUDIES ON EFFECT OF JATROPHA TANJORENSIS ON HIPPOCAMPUS AND STOMACH OF ADULT ALBINO RAT
Abstract
The increasing use of medicinal plants in traditional medicine has generated significant interest in their therapeutic benefits and safety profiles. Jatropha tanjorensis, commonly known as “hospital too far,” is widely consumed as a vegetable and used as a medicinal plant in Southern Nigeria due to its reported antihypertensive, antioxidant, antimicrobial, antimalarial, hypoglycaemic, hypolipidaemic, and haematological properties. Despite its widespread use, concerns have been raised regarding the potential toxicity of its whitish latex and the possible adverse effects associated with prolonged consumption. The cerebellum, an essential component of the central nervous system, plays a critical role in the coordination of movement, posture, balance, and motor control. Damage to cerebellar tissues may result in impaired motor functions and equilibrium. Therefore, this study investigates the potential effects of Jatropha tanjorensis leaf extract on the cerebellum of experimental rats. The study aims to evaluate possible histological alterations and toxicological effects associated with exposure to the plant extract. Findings from this research will contribute to the scientific assessment of the safety of Jatropha tanjorensis and provide useful information for its therapeutic and dietary use, with possible implications for human health.
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