MICROBIOLOGICAL ASSAY OF DIFFERENT BRANDS OF AMPICLOX ON STAPHYLOCOCCUS AUREUS FROM CASES OF FURUNCULOSIS.
Abstract
Furunculosis presents as a progressively severe staphylococcal skin infection, marked by a honey-crusted, recurrent boil that remains latent and tends to reappear in susceptible individuals. It typically affects areas with hair follicles like the neck, armpit, and buttocks. The recurrence of this condition has been linked to the presence of multi-drug resistant strains of Staphylococcus aureus. This study was therefore carried out to test the efficacy of different brands of ampiclox on isolates of Staphylococcus aureus obtained from pus from consented volunteers through a microbiological assay.
A total sum of fourty pus samples was collected from volunteers with cases of furunculosis. Biochemical tests were then carried out to identify isolates of Staphylococcus aureus present in the pus sample collected.
The results from the microbiological assay carried out using the cup plate method,
indicated that the isolates were 100% resistant to the three brands of ampiclox used and molecular characterization showed that some of the Staphylococcus aureus isolates that were resistant to the antibiotic possessed a plasmid band that could be responsible for resistance.
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