PROXIMATE, PHYTOCHEMICAL, AND ANTIBACTERIAL POTENTIAL OF N-HEXTANE EXTRACT OF MAYTENUS SENEGALENSIS
Abstract
Plants are perceived for their capacity to deliver an abundance of optional metabolites and
humankind has involved numerous species for a really long time to treat different illnesses.
However, the aim of this study is to analyze the proximate, phytochemical activity and
antibacterial properties of n-hexane of extract of Maytenus senegalensis. The proximate
composition of Maytenus senegalensis wasevaluated. High moisture was observed in
Maytenus senegalensis with the value of 12.74% while low moisture was observed with the
value of 12.70%. High ash was observed in Maytenus senegalensis with the value of 7.83%
while low ash was observed with the value of 7.79%. High crude fat was observed in
Maytenus senegalensis with the value of 6.55% while low crude fat was observed with the
value of 6.53%. High crude protein was observed to be48.23% while low crude protein was
observed to be 48.20%. The qualitative phytochemical composition of Maytenus
senegalensis was evaluated. Saponin, tannin, flavonoid, phenolics, steroid, terpenoid and
cardiac glycosides were present when screened while phlobatannin, alkaloid and
anthraquinone was not detected. The minimum inhibitory concentration and minimum
bactericidal effects of Maytenus senegalensis was evaluated. Staphylococcus aureus 29213,
Escherichia coli 25922, Pseudomonas aeroginosa 27853, Klebsiella pneumoniae 700303
and Streptococcus pyogenes 14028 were tested for inhibitory concentration and bactericidal
effects of Maytenus senegalensis. High inhibition was observed in Klebsiella pneumoniae
700303 followed by Pseudomonas aeroginosa 27853 while low inhibition was observed in
Escherichia coli 25922 and Streptococcus pyogenes 14028. In recent years, special attention
is being given on alternative safe natural bio-remedies to cure the infectious diseases
because of their less or no side effects and resistance in microbes against them. The result
reveals that 100g n-hexane extract of Maytenus senegalensis, was found very effective
against bacteria pathogens. So it may provide new leads in development of new
antimicrobial compound for the therapy of diseases and infections.
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