PREVALENCE OF CABAPENEM RESISTANT KLEBSIELLA PNEUMONIAE ISOLATED FROM LIVE BIRD MARKET IDO LOCAL GOVERNMENT IBADAN OYO STATE
Abstract
This study investigated the prevalence and antimicrobial resistance profile of Klebsiella
pneumoniae isolated from chickens, faeces, and water samples in live bird markets in Ido
Local Government, Ibadan, Oyo State, Nigeria. A total of 60 samples were collected, and
K. pneumoniae was recovered from 26 (43.3%) samples, with the highest detection in
faecal samples (40% in Apata, 30% in Kuola, and 25% in Omi), followed by chicken
(20–40%) and water (33%). Antimicrobial susceptibility testing revealed alarming
resistance to carbapenems: all isolates were resistant to ertapenem, while meropenem
showed variable but limited activity. Carbapenem-resistant K. pneumoniae (CRKP) were
detected across all sample types, including faeces (10–15%), chicken (20%), and water
(33%). Multidrug resistance was widespread, with 100% resistance to ceftriaxone,
cefepime, erythromycin, and streptomycin, and >75% resistance to tetracycline and
chloramphenicol. Partial susceptibility was retained against fluoroquinolones:
ciprofloxacin exhibited 75% activity and ofloxacin 50%, though reduced sensitivity
suggested emerging resistance. Polymicrobial growth was also observed, with Proteus
mirabilis and Pseudomonas aeruginosa co-existing alongside K. pneumoniae in market
samples. Overall, the findings highlight live bird markets as reservoirs of multidrugresistant and carbapenem-resistant K. pneumoniae, posing significant public health risks.
The detection of such resistance in poultry-associated environments underscores the
urgent need for strengthened antimicrobial stewardship, regulated antibiotic use in
livestock, and One Health–based surveillance to curb zoonotic transmission.
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