THE THERAPEUTIC POTENTIAL OF GINGER AND IT'S POSSIBLE USE IN ANTIBIOTIC RESISTANCE MICROORGANISMS
Abstract
The symbiotic relationship between humans and plant kingdom is deep-seated and intricately interwoven into the fabric of human history. As Farnsworth et al, (1985) highlighted, medicinal plants have been cornerstones in the edifice of therapeutic interventions since prehistoric times Ginger (Zingiber officinale) holds a particular esteemed position in this rich botanical tapestry. The organisms used for this research work is Salmonella and Staphylococcus aureus (MRSA). Each strain of the bacteria was collected from the stock and sub-cultured using nutrient agar at 37° for 24hrs to observe for growth visibility. A total of 0.29g of extract was added to the stock to prepare the different concentrations (100mg, 50mg,12.5mg) used. The agar diffusion test(Kirby-Bauer et al., 1959) was used to measure the effect of Antimicrobial agent (extract) against bacteria grown in culture (Salmonella and Staphylococcus aureus).Methicillin resistant staphylococcus aureus (MRSA) and Salmonella sp are shown in table 1 and 2 on ethanolic extract of Zingiber officinale can be used to treat MRSA and Salmonella infection. The result of ethanolic extract of Zingiber officinale on MRSA and Salmonella sp were active but cannot be used for the treatment of their infection. The aqueous extracts of Zingiber officinale was not reactive on the organisms. The result on table 3 of the broad spectrum antibiotics of gram negative bacteria showed that there are effective and can be used in treatment of Salmonella infection. The results on table 4 shows that broad spectrum gram positive antibiotic disc were highly reactive on MRSA.The results on table 5 shows that minimal concentration of the plant extract (Zingiber officinale) can be used in the treatment of methicillin resistant Staphylococcus aureus and Salmonella infection.Ginger extracts have demonstrated activity against certain antibiotic-resistant strains, providing a glimmer of hope in the fight against these superbugs.
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