DETERMINATION OF ALKALINE PHOSPHATASE ACTIVITY IN CHICKENS RAISED AROUND GOLD MINING AREAS

Student: Samuel Oluwapelumi Olajide
Supervisor: Dr Oluwabukola O. Babalola
HOD: Dr Oladimeji Samuel Tugbobo
Department of Biochemistry
Science and Technology
Federal Polytechnic, Ado-Ekiti, Ekiti State

Abstract

This study investigates the activity of alkaline phosphatase (ALP) in chickens raised in artisanal gold mining areas, where heavy metal toxicity poses significant health risks. Alkaline phosphatase is a critical enzyme involved in dephosphorylation processes, serving as a biomarker for liver and bone health. The presence of heavy metals such as mercury, lead, and arsenic, commonly released during gold mining activities, has been linked to elevated ALP levels, indicating potential liver damage and bone disorders. Samples were collected from different locations, revealing significant variability in ALP activity, with a p-value of

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