ANTIMICROBIAL EFFICACY OF SELECTED PLANT EXTRACT ALCHORNEA CORDIFORLIA AGAINST ACINETOBACTER BAUMANI AND KLEBSIELLA PNEUMONIA ASSOCIATD WITH HOSPITAL RELATED INFECTION
Abstract
The Study Antimicrobial Efficacy of Selected Plant Extract, Alchornea Cordiforlia against
Acinetobacter Baumanni and Klebsiella Pneumonia associated with hospital related
infections investigates the antimicrobial efficacy of Alchornea Cordiforlia leaf extracts
against Acinetobactor baumannii and Klebsiella pneumonia, pathogens responsible for
hospitalacquired infections. Methanol extracts demonstrated significant antimicrobial
activity, with the inhibitory value of Klebsiella pneumonia of 28mm at 50mg/ml and
Acinetobactor baumannii of 19mm at 50mg/ml respectively. MIC values ranging from
11mm28mm. The methanol extract exhibited higher activity against Acinetobacter
Baumannii (MIC: 12.5mg/ml. MBC: 25mg/ml) and against Klebsiella Pneumonia
(MIC:25mg/ml. MBC:12.5mg/ml). These findings suggest Alchornea Cordiforlia extracts
have potentials as natural antimicrobial agents against multiresistant bacteria, warranting
further research to optimize extraction methods, elucidate bioactive compounds, and
evaluate in vivo efficacy. The discovery of novel antimicrobial agents from plants sources
could address the growing concern of antibiotic resistance, providing alternative
therapeutic options for healthcare settings.
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