TIME INFLUENCE ON PULSE RATE FOLLOWING INTRAMUSCULARLY ADMINISTRATION OF KETAMINE IN RABBIT

The research was conducted in two weeks at Kademi under Gaya locol government area of Kano State, fifteen (15) rabbits were used and randomly divided in to five groups, with three rabbits in each groups, the rabbits were managed in deep litter cages for 16days The general anesthesia (ketamine injection) was used in the study and effect of drug was carried out at different dosage and time intervals; 10mg/kg, 15mg/kg, 20mg/kg and 15, 30, 45 and 60minutes intervals through intramuscular administration (I.M). The pulse rate was taken for three (3) days in the morning, afternoon and evening before ketamine administration as a baseline (0 minutes) and after ketamine administration the pulse rate was taken at different time intervals of different dosages in the morning, afternoon and evening in the same days. The 10mg/kg and 15 mg/kg dosage of ketamine decreased rabbits heart beats/min in the morning administration compared to afternoon and evening administered where it increases, while the 20mg/kg dosage of ketamine increased rabbits heart beats/min in the morning and afternoon administration compared to evening administration where it decreased in beats/min.